SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2(b) (Amendment No. 1) (1) Discovery Partners International, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 25467510 (CUSIP Number) December 31, 2001 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: [_] Rule 13d-1(b) [_] Rule 13d-1(c) [X] Rule 13d-1(d) (1) The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

13G - ----------------------- ----------------------- CUSIP No. 25467510 Page 2 of 17 pages. - ----------------------- ----------------------- - -------------------------------------------------------------------------------- 1. Name of Reporting Person I.R.S. Identification No. of Above Persons (Entities Only) Mayfield VIII, a California Limited Partnership - -------------------------------------------------------------------------------- 2. Check the Appropriate Box if a Member of a Group (a) [_] (b) [X] - -------------------------------------------------------------------------------- 3. SEC Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization California - -------------------------------------------------------------------------------- Number of 5. Sole Voting Power Shares -0- ---------------------------------------------------------------- Beneficially 6. Shared Voting Power Owned By -0- ---------------------------------------------------------------- Each 7. Sole Dispositive Power Reporting -0- ---------------------------------------------------------------- Person 8. Shared Dispositive Power With -0- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person -0- - -------------------------------------------------------------------------------- 10. Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares [_] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row (9) 0% - -------------------------------------------------------------------------------- 12. Type of Reporting Person PN - --------------------------------------------------------------------------------

13G - ----------------------- ----------------------- CUSIP No. 25467510 Page 3 of 17 pages. - ----------------------- ----------------------- - -------------------------------------------------------------------------------- 1. Name of Reporting Person I.R.S. Identification No. of Above Persons (Entities Only) Mayfield VIII Management, L.L.C. - -------------------------------------------------------------------------------- 2. Check the Appropriate Box if a Member of a Group (a) [_] (b) [X] - -------------------------------------------------------------------------------- 3. SEC Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization Delaware - -------------------------------------------------------------------------------- Number of 5. Sole Voting Power Shares -0- ---------------------------------------------------------------- Beneficially 6. Shared Voting Power Owned By 5,365 ---------------------------------------------------------------- Each 7. Sole Dispositive Power Reporting -0- ---------------------------------------------------------------- Person 8. Shared Dispositive Power With 5,365 - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person 5,365 - -------------------------------------------------------------------------------- 10. Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares [_] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row (9) 0% - -------------------------------------------------------------------------------- 12. Type of Reporting Person OO - --------------------------------------------------------------------------------

13G - ----------------------- ----------------------- CUSIP No. 25467510 Page 4 of 17 pages. - ----------------------- ----------------------- - -------------------------------------------------------------------------------- 1. Name of Reporting Person I.R.S. Identification No. of Above Persons (Entities Only) Mayfield Associates Fund II, a California Limited Partnership - -------------------------------------------------------------------------------- 2. Check the Appropriate Box if a Member of a Group (a) [_] (b) [X] - -------------------------------------------------------------------------------- 3. SEC Use Only - -------------------------------------------------------------------------------- 4. Citizenship or Place of Organization California - -------------------------------------------------------------------------------- Number of 5. Sole Voting Power Shares -0- ------------------------------------------------------------------ Beneficially 6. Shared Voting Power Owned By -0- ------------------------------------------------------------------ Each 7. Sole Dispositive Power Reporting -0- ------------------------------------------------------------------ Person 8. Shared Dispositive Power With -0- - -------------------------------------------------------------------------------- 9. Aggregate Amount Beneficially Owned by Each Reporting Person -0- - -------------------------------------------------------------------------------- 10. Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares [_] - -------------------------------------------------------------------------------- 11. Percent of Class Represented by Amount in Row (9) 0% - -------------------------------------------------------------------------------- 12. Type of Reporting Person PN - --------------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 5 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) Yogen K. Dalal - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 153 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 153 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 153 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - ------------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 6 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) F. Gibson Myers, Jr. - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 155 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 155 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 155 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 7 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) Kevin A. Fong - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 19 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 19 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 19 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 8 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) William D. Unger - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 39 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 39 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 39 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 9 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) Wendell G. Van Auken, III - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 152 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 152 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 152 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 10 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) Michael J. Levinthal - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF -0- SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING -0- PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. -0- - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 11 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) A. Grant Heidrich, III - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 154 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 154 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 154 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

13G - ----------------------- ---------------------- CUSIP No. 25467510 Page 12 of 17 pages. - ----------------------- ---------------------- - ------------------------------------------------------------------------------ Name of Reporting Person 1. I.R.S. Identification No. of Above Persons (Entities Only) Wende S. Hutton - ------------------------------------------------------------------------------ Check the Appropriate Box if a Member of a Group 2. (a) [_] (b) [X] - ------------------------------------------------------------------------------ SEC Use Only 3. - ------------------------------------------------------------------------------ Citizenship or Place of Organization 4. U.S. - ------------------------------------------------------------------------------ Sole Voting Power 5. NUMBER OF 6,154 SHARES ----------------------------------------------------------- Shared Voting Power BENEFICIALLY 6. OWNED BY -0- ----------------------------------------------------------- EACH Sole Dispositive Power 7. REPORTING 6,154 PERSON ----------------------------------------------------------- Shared Dispositive Power WITH 8. -0- - ------------------------------------------------------------------------------ Aggregate Amount Beneficially Owned by Each Reporting Person 9. 6,154 - ------------------------------------------------------------------------------ Check Box if the Aggregate Amount in Row (9) Excludes Certain Shares 10. [_] - ------------------------------------------------------------------------------ Percent of Class Represented by Amount in Row (9) 11. 0% - ------------------------------------------------------------------------------ Type of Reporting Person 12. IN - -----------------------------------------------------------------------------

Item 1. (a) Name of Issuer: Discovery Partners International, Inc. (b) Address of Issuer's Principal Executive Offices: 9640 Towne Centre Drive San Diego, CA 92121 Item 2. (a) Name of Persons Filing: Mayfield VIII, a California Limited Partnership Mayfield VIII Management, L.L.C. Mayfield Associates Fund II, a California Limited Partnership Yogen K. Dalal F. Gibson Myers, Jr. Kevin A. Fong William D. Unger Wendell G. Van Auken, III Michael J. Levinthal A. Grant Heidrich, III Wende S. Hutton (b) Address of Principal Business Office: c/o Mayfield Fund 2800 Sand Hill Road Menlo Park, CA 94025 (c) Citizenship: Mayfield VIII and Mayfield Associates Fund II are California Limited Partnerships. Mayfield VIII Management, L.L.C. is a Delaware Limited Liability Company. The individuals listed in Item 2(a) are U.S. citizens. (d) Title of Class of Securities: Common Stock, $0.001 par value (e) CUSIP Number: 25467510 Page 13 of 17 pages.

Item 3. If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b) or (c), check whether the person filing is a: Not applicable Item 4. Ownership. The information regarding ownership as set forth in Items 5-9 of Pages 2-12 hereto, is hereby incorporated by reference. Shares beneficially owned by each individual reporting person are held as trustee of a trust for the benefit of such reporting person and members of his or her family. Item 5. Ownership of Five Percent or Less of a Class. If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following [X]. Item 6. Ownership of More than Five Percent on Behalf of Another Person. Not applicable. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person. Not applicable. Item 8. Identification and Classification of Members of the Group. Not applicable. Item 9. Notice of Dissolution of Group. Not applicable. Item 10. Certification. Not applicable. Page 14 of 17 pages.

SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Date: February 13, 2002 MAYFIELD VIII A California Limited Partnership By: Mayfield VIII Management, L.L.C. Its General Partner By: /s/ James T. Beck ------------------------------------------ James T. Beck, Authorized Signatory MAYFIELD VIII MANAGEMENT, L.L.C. By: /s/ James T. Beck ------------------------------------------ James T. Beck, Authorized Signatory MAYFIELD ASSOCIATES FUND II A California Limited Partnership By: /s/ James T. Beck ------------------------------------------ James T. Beck, Authorized Signatory YOGEN K. DALAL By: /s/ James T. Beck ------------------------------------------ James T. Beck, Attorney In Fact F. GIBSON MYERS, JR. By: /s/ James T. Beck ------------------------------------------ James T. Beck, Attorney In Fact KEVIN A. FONG By: /s/ James T. Beck ------------------------------------------ James T. Beck, Attorney In Fact WILLIAM D. UNGER By: /s/ James T. Beck ------------------------------------------ James T. Beck, Attorney In Fact WENDELL G. VAN AUKEN, III By: /s/ James T. Beck ------------------------------------------ James T. Beck, Attorney In Fact Page 15 of 17 pages.

MICHAEL J. LEVINTHAL By: /s/ James T. Beck ------------------------------------- James T. Beck, Attorney In Fact A. GRANT HEIDRICH, III By: /s/ James T. Beck ------------------------------------- James T. Beck, Attorney In Fact WENDE S. HUTTON By: /s/ James T. Beck ------------------------------------- James T. Beck, Attorney In Fact Page 16 of 17 pages.

EXHIBIT INDEX Exhibit 1 - "JOINT FILING AGREEMENT" is hereby incorporated by reference to Exhibit 1 to the Statement on Schedule 13G dated February 13, 2001. Exhibit 2 - "POWERS OF ATTORNEY" is hereby incorporated by reference to Exhibit 2 to the Statement on Schedule 13G dated February 13, 2001. Page 17 of 17 pages.